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A large hurdle in drug development is that, although many therapeutics show promising results in rodent models, the therapeutic value does not always translate to human patients in clinical trials. There is a need to look for a biomarker that is translational, objective and quantitative, in order to maximize chances of success.
EEG Phenotyping consists in identifying, in an animal model, an abnormal brain-wave pattern relevant to the disorder of interest, whether it be common brain disorders or orphan diseases.