SCIENTIFIC PUBLICATIONS AND POSTERS

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Publication: Differential Effects of Antiepileptic Drugs on Focal Seizures in the Intrahippocampal Kainate Mouse Model of Mesial Temporal Lobe Epilepsy

Focal Epilepsy

Publication: Pronounced Antiepileptic Activity of the Subtype-Selective GABAA -Positive Allosteric Modulator PF-06372865 in the GAERS Absence Epilepsy Model

Generalized Absence Epilepsy.
A joint publication SynapCell x Pfizer.

Publication: BAER-101, a selective potentiator of α2- and α3-containing GABAA receptors, fully suppresses spontaneous cortical spike-wave discharges in Genetic Absence Epilepsy Rats from Strasbourg (GAERS)

Generalized Absence Epilepsy.

Poster: Pronounced Antiepileptic Activity of the Subtype-Selective GABAA Positive Alosteric Modulator PF-06372865 in the GAERS Model

Assessing the antiepileptic effect of PF-06372865, a newly developed GABAA modulator, developed by Pfizer, in a preclinical model of absence seizures, the GAERS rat.

Poster: The SynapCell MTLE Model, a Predictive Model of Focal Epilepsy for Drug Discovery

A powerful preclinical tool accelerating drug-resistant epilepsy research. This MTLE model accurately mirrors human focal Epilepsy capturing drug sensitivities and crucial EEG biomarkers.

Poster: Pharmacological Assessment of Anti-Seizure Medications in the Rat Amygdala-Kindling Model

This study intends to highlight translational and predictive aspects of the amygdala-kindling model as a potential asset for characterizing new entities with improved tolerability and efficacy.